Results Our expression data came from 51 normal samples and 383 tumor samples Supplementary Table S1.
We also used MutationMapper tools to depict the mutation landscape of each hub gene.
Xinqiang Song: Writing—review and editing.
The up-regulated DEGs were involved mainly in nuclear division, cell cycle regulation, chromosome segregation, and DNA replication D.
Lei Wang: Data curation.
D GO analysis of functional enrichment of up-regulated genes.
Immunohistochemical validation of OSBPL3 as a hub gene We further validated the clinical significance of OSBPL3 as a hub gene using immunohistochemistry.
Written informed consent for tissue donation, which clearly stated the purpose of our study, was obtained from all of the patients.