Louis-Dreyfus' film roles have included Hannah and Her Sisters 1986 , National Lampoon's Christmas Vacation 1989 Deconstructing Harry 1997 and Enough Said 2013 She has voiced roles in several animated films, including A Bug's Life 1998 and Planes 2013.
Louis-Dreyfus broke into comedy as a performer in The Practical Theatre Company in Chicago, Illinois, which led to her casting in the sketch show, Saturday Night Live, from 1982 to 1985.
Louis-Dreyfus has received seven Emmy Awards, with a total of 21 nominations throughout her career.
In 2016, Time named Louis-Dreyfus one of the 100 most influential people in the world on the annual Time 100 list.
She has also received a Golden Globe Award, six Screen Actors Guild Awards, five American Comedy Awards, and two Critics' Choice Television Awards.
She is known for her work in television comedy, including Saturday Night Live 1982—85 , Seinfeld 1989—98 , The New Adventures of Old Christine 2006—10 , and Veep 2012—present.
Her breakthrough came in 1990 with a nine-season run, playing Elaine Benes on Seinfeld, one of the most critically and commercially successful sitcoms of all time.