They were married from 2013 to 2016.
The Harley Quinn voice actress recently announced her split with husband Karl Cook whom she married in 2018.
The actress, 35, was in character as Cassie while wearing a purple-and-black top with her hair in a shag style.
The two met at a horse show in 2016.
There is no set release day for the movie yet.
In addition, the actress will star in The Man From Toronto which has a January 14, 2022 release date.
The Man From Toronto follows an average Joe who gets mistaken for a deadly assassin at an Airbnb.
Split: Despite her career success, Cuoco's personal life hit a major snag recently.