The program was up for a 10-year renewal and was thought by supporters to allow the city to remain competitive in recruiting job-creating businesses to the area.
Petersburg's health committee did not immediately respond to written questions.
The two amendments approved by voters were those considered to be among the least consequential.
Amendment 3 would have created a Chief Equity Officer position to oversee equity initiatives in the city, as well as establish an equity plan.
He was the second Black person elected to that panel.
This sign is ruled by Mars, the dynamic red planet named after the Roman god of war.
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Petersburg has recorded 17,069 coronavirus cases and a total of 240 deaths.